Browsing by Author "Disli, Ali"
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Design, Synthesis, and Evaluation of Heat Shock Protein 90 Inhibitors in Human Breast Cancer and Its Metastasis
Gumus, Mehmet; Ozgur, Aykut; Tutar, Lutfi; Disli, Ali; Koca, Irfan; Tutar, Yusuf (BENTHAM SCIENCE PUBL LTD, 2016)Background: Despite development of novel cancer drugs, invasive ductal breast carcinoma and its metastasis are still highly morbid. Therefore, new therapeutic approaches are being developed and Hsp90 is an important target ... -
A Novel Approach to Inhibit Heat Shock Response as Anticancer Strategy by Coumarine Compounds Containing Thiazole Skeleton
Koca, Irfan; Gumus, Mehmet; Ozgur, Aykut; Disli, Ali; Tutar, Yusuf (BENTHAM SCIENCE PUBL LTD, 2015)Inhibition of the Hsp90 function is an essential therapeutic approach and several inhibitors were designed as anti-cancer agents. These inhibitors are ATPases and they aim to deregulate Hsp90 folding function. ATPase ...